RESOURCE

RESOURCE

01

Pressure Cycling Technology

Barocyclers are products of Pressure Biosciences Inc. The barocyclers NEP 2320 are optimized for productive biopsy tissue analysis.

02

Mass Spectrometry

We have several MS instruments of different vendors (Thermo Orbitrap HF, Sciex, Bruker Tims TOF Pro )

03

Proteomic Big Data

We analyze mass spectrometry-based proteomic big data with a variety of software tools.

04

Cloud Computing

We developed cloud based tool to anlayze proteomic big data. e.g. BatchServer is a web server for batch effects evaluation, visualization, and correction. Check our github: BatchServer

DIA Resource

01 T. Xu et al., ProLuCID: An improved SEQUEST-like algorithm with enhanced sensitivity and specificity. J Proteomics 129, 16-24 (2015)

02 S. Adhikari et al., A high-stringency blueprint of the human proteome. Nat Commun 11, 5301 (2020).

03 R. Aebersold, M. Mann, Mass spectrometry-based proteomics. Nature 422, 198-207 (2003).

04 A. F. Altelaar, J. Munoz, A. J. Heck, Next-generation proteomics: towards an integrative view of proteome dynamics. Nat Rev Genet 14, 35-48 (2013).

05 D. Amodei et al., Improving Precursor Selectivity in Data-Independent Acquisition Using Overlapping Windows. J Am Soc Mass Spectrom 30, 669-684 (2019).

06 D. B. Bekker-Jensen et al., Rapid and site-specific deep phosphoproteome profiling by data-independent acquisition without the need for spectral libraries. Nat Commun 11, 787 (2020).

07 L. Bichmann et al., DIAproteomics: A multi-functional data analysis pipeline for data-independent-acquisition proteomics and peptidomics. bioRxiv, 2020.2012.2008.415844 (2020).

08 I. Bludau, R. Aebersold, Proteomic and interactomic insights into the molecular basis of cell functional diversity. Nat Rev Mol Cell Biol 21, 327-340 (2020).

09 K. Buczak et al., Spatially resolved analysis of FFPE tissue proteomes by quantitative mass spectrometry. Nat Protoc 15, 2956-2979 (2020).

10 M. Choi et al., MassIVE.quant: a community resource of quantitative mass spectrometry-based proteomics datasets. Nat Methods 17, 981-984 (2020).