压力循环技术
Barocyclers 是 Pressure Biosciences Inc 的产品。barocyclers NEP 2320 适用于批量分析活检组织样本。
质谱仪
我们拥有不同品牌的质谱仪 (Thermo Orbitrap HF, Sciex TripleTOF )
蛋白质组学大数据
我们使用各种软件工具分析基于质谱的蛋白质组大数据。
云计算
我们开发了基于云的分析蛋白质组大数据的工具。例如 BatchServer 是一个可 用于批次效应评估、可视化和校正的在线服务器。查看我们的 Github:https://github.com/guomics-lab/
DIA Resource
01 T. Xu et al., ProLuCID: An improved SEQUEST-like algorithm with enhanced sensitivity and specificity. J Proteomics 129, 16-24 (2015)
02 S. Adhikari et al., A high-stringency blueprint of the human proteome. Nat Commun 11, 5301 (2020).
03 R. Aebersold, M. Mann, Mass spectrometry-based proteomics. Nature 422, 198-207 (2003).
04 A. F. Altelaar, J. Munoz, A. J. Heck, Next-generation proteomics: towards an integrative view of proteome dynamics. Nat Rev Genet 14, 35-48 (2013).
05 D. Amodei et al., Improving Precursor Selectivity in Data-Independent Acquisition Using Overlapping Windows. J Am Soc Mass Spectrom 30, 669-684 (2019).
06 D. B. Bekker-Jensen et al., Rapid and site-specific deep phosphoproteome profiling by data-independent acquisition without the need for spectral libraries. Nat Commun 11, 787 (2020).
07 L. Bichmann et al., DIAproteomics: A multi-functional data analysis pipeline for data-independent-acquisition proteomics and peptidomics. bioRxiv, 2020.2012.2008.415844 (2020).
08 I. Bludau, R. Aebersold, Proteomic and interactomic insights into the molecular basis of cell functional diversity. Nat Rev Mol Cell Biol 21, 327-340 (2020).
09 K. Buczak et al., Spatially resolved analysis of FFPE tissue proteomes by quantitative mass spectrometry. Nat Protoc 15, 2956-2979 (2020).
10 M. Choi et al., MassIVE.quant: a community resource of quantitative mass spectrometry-based proteomics datasets. Nat Methods 17, 981-984 (2020).
