Dr. Tiannan Guo completed his clinical medicine training (1999–2006) at Tongji Medical College, Huazhong University of Science and Technology, and simultaneously pursued studies in biology (2001–2005) at Wuhan University. Subsequently, he earned a Ph.D. in cancer proteomics (2008–2012) in Singapore and conducted postdoctoral research at ETH Zurich (2012-2017). After a brief tenure as Scientific Director of ProCan, Children’s Medical Research Institute, The University of Sydney School in 2017, Dr. Guo relocated to Westlake University in August 2017 as a tenure-track Assistant Professor, achieving promotion to tenured Associate Professor in January 2023. He also directs the Westlake Center for Intelligent Proteomics at Westlake Laboratory.
Dr. Guo and his team have developed high-throughput proteomic technologies for micro-scale tissue samples and spatial subcellular proteomics, supporting efforts to address major health challenges including cancer, infectious diseases, and aging. They have constructed MassNet, a billion-scale AI-friendly mass spectrometry corpus, and developed a suite of proteome-focused pre-trained models. In addition, Dr. Guo has led the development of a strategic roadmap for artificial intelligence-driven proteomics, proposed a novel framework for constructing AI-enabled virtual cells, and established ProteinTalks—the first foundational virtual cell model based on perturbed proteomics. His team has also developed multiple clinical kits based on mass spectrometry proteomics, and initiated the international consortiums for AI Proteomics and virtual yeast.
Dr. Guo holds the presidency of the Chinese Proteomics Society, and serves as a Council Member of the Human Proteome Organization (HUPO). He is also an Associate Editor of Molecular & Cellular Proteomics, an Editorial Board Member of Genomics, Proteomics & Bioinformatics and Cell Systems, an Advisory Expert of Cell Reports Medicine, and a Scientific Advisor for Vita and Molecular Systems Biology.